BestsellerPROBIOTIC OPTIBIOME
A clinically-dosed synbiotic that relieves bloating, supports regularity, and nurtures whole-body health, engineered to survive and reach the gut alive.
$39.90
30-day supply
Feel the difference of a truly healthy gut.


Unlike many probiotics, OptiBiome makes it to the gut alive.
Most probiotics die in stomach acid. Our MAKTREK Bi-Pass technology shields the strains and an FOS prebiotic fiber feeds them, so they arrive alive in the colon.
Benefits that build over time
Real results you can feel, and that keep compounding the longer you stay consistent.
- 7 Days
Reduces bloating & gas
- Less rumbling and gut discomfort
- Eases bloating after meals
- Strains arrive alive and start colonizing
- 2 Weeks
Supports regularity
- More consistent, comfortable digestion
- Improves stool quality and frequency
- Reduces occasional constipation
- 1 Month+
Whole-body health
- Supports immune balance through the gut
- Clearer skin via the gut-skin axis
- Better nutrient synthesis and overall wellbeing

How to use



A clinically-dosed synbiotic for transformative gut benefits.
Formulated with clinically-studied, bioavailable ingredients and screened as a full formula for purity and potency.

How OptiBiome Compares
Loved by members
4.8
Based on 4,120 reviews
The bloating is GONE
I've dealt with end-of-day bloating for years, to the point where I kept separate jeans for evenings. Two weeks on OptiBiome and I genuinely forgot about it until my old jeans fit at 8pm. I've tried Align and a fridge probiotic from Whole Foods before, neither did this. The 40 billion CFU plus the acid protection thing seems to actually matter.
Post-antibiotics gut rescue
Took two rounds of antibiotics for a sinus infection and my digestion was a disaster afterwards. My GI doc said get a multi-strain probiotic with research behind it. A month on this and I'm fully back to normal, regular every morning like clockwork. No refrigeration needed was a bonus since I travel for work weekly.
Took about 3 weeks, then it clicked
Heads up: the first week I was actually a bit gassier, which apparently is normal while your gut adjusts. Week two it settled, week three onwards I've been more regular than I've been in years. Stick with it past the adjustment phase. Four stars only because that first week was rough.
IBS-C sufferer, this is my third bottle
Not a cure and I still watch my trigger foods, but the difference in my baseline is real. Less cramping, way less unpredictable urgency, and I'm not thinking about my stomach all day anymore. I specifically picked this one because the strains are named with the exact codes (La-14, Bl-04 etc) instead of a vague blend.
My skin cleared up?? not even mad
Bought it for digestion, which improved within a couple weeks. The surprise was my skin. The little breakouts along my chin that I'd been blaming on hormones calmed way down after about 6 weeks. Gut-skin axis is apparently real. One capsule a day, easy to swallow, no aftertaste or burps.
Tried the cheap ones first, lesson learned
I cycled through three drugstore probiotics that did nothing. Turns out most strains die in stomach acid before they get anywhere, which explains a lot. The MAKTREK coating on these apparently gets them through. All I know is within a month my digestion is quieter, no more embarrassing gurgling in meetings, and I feel lighter after meals.
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